BioTechnology: An Indian Journal
ISSN (PRINT): 0974-7435

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Chromatin

Chromatin is a complex of DNA and protein found in eukaryotic cells.[1] Its essential capacity is bundling long DNA particles into progressively minimal, denser structures. This keeps the strands from getting tangled and furthermore assumes significant jobs in fortifying the DNA during cell division, forestalling DNA harm, and managing quality articulation and DNA replication. During mitosis and meiosis, chromatin encourages legitimate isolation of the chromosomes in anaphase; the trademark states of chromosomes obvious during this stage are the aftereffect of DNA being curled into exceptionally consolidated chromatin. The essential protein segments of chromatin are histones, which tie to DNA and capacity as "stays" around which the strands are wound. All in all, there are three degrees of chromatin association: DNA folds over histone proteins, framing nucleosomes and the alleged "dots on a string" structure (euchromatin). Various histones wrap into a 30-nanometer fiber comprising of nucleosome clusters in their most conservative structure (heterochromatin).More significant level DNA supercoiling of the 30-nm fiber creates the metaphase chromosome (during mitosis and meiosis). Numerous life forms, be that as it may, don't follow this association conspire. For instance, spermatozoa and avian red platelets have more firmly pressed chromatin than most eukaryotic cells, and trypanosomatid protozoa don't consolidate their chromatin into obvious chromosomes by any means. 

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Citations : 875

BioTechnology: An Indian Journal received 875 citations as per Google Scholar report

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