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Aging Population Impact Factor

Population ageing is an increasing median age in a population due to declining fertility rates and rising life expectancy.  The age-related decline in immunity results not only in increased susceptibility to infection but also reduces the prophylactic efficacy of vaccinations. The two combined lead to increased risk of infections and mortality in older adults. Current research is indicating routes to improved vaccination regimes in older adults, such as adjuvants focused upon aspects of the immune response that remain intact, or simple interventions such as the time of day the vaccine is given or the use of booster vaccinations in old subjects. Further research is, however, needed to optimize vaccination protocols for older adults and provide the evidence based for altered health policy in this area.  

High Impact List of Articles

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