Abstract
Synthesis and antimicrobial activity of some benzimidazole derivatives
Author(s): D.N.Patil, S.C.Chaturvedi, D.L.Kale, R.B.Kakde, S.B.DahikarA series of substituted benzimidazole compounds were synthesized by phase transfer catalyst (PTC) method using quaternary ammonium salt. Reaction has been carried out by conventional method in inert gas. Synthesized compoundswere confirmed by IR, NMR,mass spectral and elemental analysis. The synthesized compounds were screened for their antibacterial and antifungal activity using paper disc diffusion method against some microorganism such as Escherichia coli, Bacillus pumilis, Staphylococcus aureus, Shigella sonnei, Proteus vulgaris, Pseudomonas aeruginosa, Aspergillus niger, Candida albicans. Almost all compounds shows potent antibacterial and antifungal activity.
