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Eno1p

Immunofluorescence microscopy observed the display of Eno1p on the cell surface of BY4741/eno1 cells harboring the plasmid. For quantitative chemical analysis of the relative amounts of Eno1p displayed on the surface of yeast cells during cultivation during a liquid medium, the fluorescence of yeast cells bound with AlexaFluor488- labeled IgG was measured. Eno1p-displaying yeast cells were grown for oral administration to mice; cells 1 displayed an outsized number of Eno1p- fusion proteins on their surfaces. ENO1p overexpression has been associated with multiple tumors, including glioma, neuroendocrine tumors, neuroblastoma, pancreatic cancer, prostate cancer, cholangiocarcinoma, thyroid carcinoma, lung cancer, hepatocellular carcinoma, and breast cancer.In many of these tumors, ENO1p promoted cell proliferation by regulating the PI3K/AKT signaling pathway and induced tumorigenesis by activating plasminogen.

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Citations : 378

Analytical Chemistry: An Indian Journal received 378 citations as per Google Scholar report

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