BioTechnology: An Indian Journal
ISSN (PRINT): 0974-7435

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Circulating Tumor Cells

Circulating tumor cells (CTCs) are a rare subset of cells found inside the blood of patients with solid tumors, which function as a seed for metastases. Cancer cells metastasize thru the bloodstream both as unmarried migratory CTCs or as multicellular groupings CTC clusters. The CTCs preserve number one tumor heterogeneity and mimic tumor properties, and can be considered as scientific biomarker, preclinical version, and therapeutic goal. The potential clinical software of CTCs is being a component of liquid biopsy. CTCs also are true applicants for generating preclinical fashions, mainly 3D organoid cultures, which can be implemented in drug screening, disorder modeling, genome enhancing, tumor immunity, and organoid biobanks. In this review, we summarize contemporary information on the cost and promise of evolving CTC technology and spotlight modern studies on CTCs in liquid biopsy, tumor metastasis, and organoid preclinical models.  

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Citations : 875

BioTechnology: An Indian Journal received 875 citations as per Google Scholar report

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