Abstract

Synthesis of some azetidinones with coumarinyl moiety and their antimicrobial activity

Author(s): Brish.M.Sharma, M.V.Parsania, A.J.Baxi

Compounds bearing azetidinone moiety having -lactamring which is an antibiotic still in the list of the prescription[1] are endowed with a variety of biological activities such as sedative, hypnotic, anticonvulsant[2,3], herbicidal[ 4] and antibacterial[5]. Looking over to these properties it was contemplated to synthesis some Azetidinones having coumarin moiety type(II) which may enhance the biological activity with least side effect. The structures of type (II) have been characterized by the elemental analysis and the spectral data. The compounds were screened for their antimicrobial activity using different strains of Bacteria’s and Fungi.