Synthesis of dithiocarbamate ligand and study of their biological properties

Author(s): Hafezeh Nabipour

Dithiocarbamates as ligands are well known to bind strongly and selectively to manymetal ions, so in the past fewyears self-assembly directed by metal–dithiocarbamate coordination have emerged as a useful supramolecular methodology for the preparation of macrocycles, cages, catenanes, and nanoparticles. Dithiocarbamate (DTC) ligands are known for their antifungal, antibacterial and biocide activity. They formcomplexes with transition metals, leading to the stabilization of a wide range of oxidation states. These complexes have found applications in diverse areas such as materials science and medicine. The in situ generated dithiocarbamate formed by the reaction of an diamine and aldehyde and carbon disulfide in the presence of triethylamine. The antibacterial activity of dithiocarbamte tested againstmicroorganism.

Share this