Synthesis and spectral characterization of related compounds of Losartan potassium, an anti-hypertensive drug substance

Author(s): D.P.Lokamaheshwari, G.Naveeenchandra Reddy, Bollikonda Satyanarayana

Losartan potassium (1) is a known anti-hypertensive drug substance, recently appeared in the European pharmacopoeia with the several process related compounds/impurities. Out of (12) related compounds (6) were synthesized and characterized based on IR, NMR and MS spectral data, and same thing was described in this article.

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