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Abstract

Synthesis and characterization of the new type of tetrazoles containing barbiturates.

Author(s): Mahdokht Rezazadeh, Amin Azimian Freidani

Reaction of 4-cyano benzaldehyde with sodiumazide in presence of ammoniumChloride in dimethyl formamide under reflux conditions gave 4-(1Htetrazole- 5-yl)benzaldehyde, which was condense with barbiturates under knoevenagel condensations to give newsubstituted derivatives of tetrazoles with good yield.


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