Abstract
Synthesis and characterization of novel isoxazolyl and pyrazolyl 2,3, 4, 9 tetrahydro-1H-carbazoles and their antimicrobial studies
Author(s): T.Surendiran, S.Balasubramanian, D.SivarajA new family of Isoxazolyl 2,3,4,9 -tetrahydro-1H-carbazoles (3a-g) and Pyrazolyl 2,3,4,9-tetrahydro -1H-carbazoles(4a-g)were individually derived using 2,3,4,9- tetrahydro-1H-carbazolyl chalcones(2a-g) by cyclizationwith hydroxylamine sulfate and hydrazine hydrate respectively. 2,3,4,9 tetrahydro- 1H-carbazolyl chalcones were derived from 2,3,4,9- tetrahydro-1H-carbazole by acetylation and followed by aldol condensation .These products were characterized by IR, NMR,MASS spectra and by elemental analysis . All the end products were Screened for antibacterial and antifungal activities.
