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Abstract

Synthesis and biological screening of 2-(4テッツ?ツ「-chlorophenyl)-6-methyl-3-(3テッツ?ツイ- aryl -1テッツ?ツイ-acetyl/phenyl -4テッツ?ツイ,5-dihydropyrazol-5テッツ?ツイ-yl)- imidazo[1, 2-a]pyridines

Author(s): V.V.Bhuva, V.N.Patolia, A.U.Patel, D.M.Purohit

2-(4テδッテや堙つ「-chlorophenyl)-6-methyl-3-(3テδッテや堙つイ-aryl-1テδッテや堙つイacetyl-4テδッテや堙つイ,5テδッテや堙つイ-dihydropyrazol-5テδッテや堙つイ- yl)imidazo [1,2-a] pyridines (4a-4l); 2-(4'-chlorophenyl)-6-methyl-3-(3テδッテや堙つイ-aryl- 1テδッテや堙つイ-phenyl-4テδッテや堙つイ,5テδッテや堙つイ dihydropyrazol-5テδッテや堙つイ-yl) imidazo [1, 2-a] pyridines(5a-5l) have been synthesized. The products have been assayed for their biological activity against Gram +ve,Gram テ窶堙や砺e bacteria and fungi. Some of the products showed moderate activity in concentration 50テδッテつテつュg/ml. The structures of the products have been elucidated by IR, 1HNMR, Mass spectral data, elemental analysis and thin layer chromatography.


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