Abstract

Synthesis and biological screening 2-[(4'-chlorophenyl)-6-methylimidazo [1, 2 - a] pyridin - 3 - yl] methylene - 1" - aryl -2" phenyl-5"-oxo-imidazolines

Author(s): D.M.Purohit, V.V.Bhuva

2-[(4'-chlorophenyl)-6-methylimidazo[1,2-a]pyridin-3-yl]methylene-1"-aryl- 2"-phenyl-5"-oxo-imidazolines. (4a-4l) have been synthesized. The products have been assayed for their biological activity against Gram+ve,Gram –ve bacteria and fungi. Some of the products showed moderate activity in concentration 50µg/ml. The structures of the products have been elucidated by IR,1HNMR, Mass spectral data, elemental analysis and thin layer chromatography