Abstract
Synthesis and Biological investigation of some new 3, 5-diaryl-6- carboethoxy, 6-acetoxy cyclohexenone and indazole derivatives.
Author(s): Bhaskar S.Dawane, Shankaraiah G.Konda, M.Shaikh Baseer, Yeshwant B.VibhuteThe á, â- unsaturated carbonyl compounds have been converted into the corresponding 3, 5-diaryl-6-carboethoxy, and 6-acetoxy cyclohex-2-en-1- ones by the Michael condensation with ethyl acetoacetate and acetyl acetone in presence of ethanolic piperidine. These 6-carboethoxy cyclohex-2- en-1-ones (II) treated with hydrazine hydrate in ethanolic-acetic acid to yield corresponding indazoles (IV). The newly synthesized compounds were established on the basis of spectral analysis and have been screened for their antibacterial activity.
