Abstract

Synthesis and biological evaluation of some new 5-oxo-imidazolines

Author(s): D.P.Bhoot, H.G.Sangani, R.C.Khunt, H.H.Parekh

The target compounds 1-aryl-2-phenyl-4-[5’-(m,p-dichlorophenyl)-2’-furylidene]-5-oxo-imidazolines (3a-o) have been synthesized by the condensation of 4-oxo-2-phenyl-5-[5’-(m,p-dichlorophenyl)-2’-furylidene]-oxazole (2)with different arylamines in dry pyridine. All the products have been evaluated for their antimicrobial activity towards different strains of bacteria and fungi and antitubercular activity towards Mycobacterium tuberculosis H37 Rv.