Abstract

Simple and convenient synthesis of 2-(Substituted-benzylsulfanyl)-1H-benzimidazoles

Author(s): D.Shobha, M.Adharvana Chari, K.Mukkanti

A simple and convenient procedure for the preparation of 2-(substituted – benzimidazoles by the reaction of 2-mercapto benzimidazole and benzyl bromides in methanol / sodium carbonate condition has been reported. This new method consistently has the advantage of excellent yields (87- 95%) and short reaction time (3 h) at reflux temperature.