QSAR study of aroyl-pyrrolyl-hydroxy-amide (APHA)derivatives with the help of PM3 based descriptors

Dinesh Kumar; R.N.Singh; Sunil Kumar

Organic Chemistry: An Indian Journal
ISSN (PRINT): 0974-7516

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Abstract

QSAR study of aroyl-pyrrolyl-hydroxy-amide (APHA)derivatives with the help of PM3 based descriptors

Author(s): Dinesh Kumar, R.N.Singh, Sunil Kumar

In this present work, we have taken a ten Aroyl-Pyrrolyl-Hydroxy-Amide derivatives and developed QSAR models with the help of Quantumchemical descriptors.The values of quantum chemical descriptors are directly obtained by CAChe software. The first set containsPyrrole derivatives & the correlation coefficient of this set is above 0.81.