Polymer (PVP) Supported Ferric Chloride: An Efficient And Recyclable Heterogenous Catalyst For One-Pot Synthesis Of 4(3H)-Quinazolinones Under Solvent Free Conditions

K.Mukkanti; D.Shobha; M.Adharvana Chari; Prakash MMS Kinthada

Organic Chemistry: An Indian Journal
ISSN (PRINT): 0974-7516

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Abstract

Polymer (PVP) Supported Ferric Chloride: An Efficient And Recyclable Heterogenous Catalyst For One-Pot Synthesis Of 4(3H)-Quinazolinones Under Solvent Free Conditions

Author(s): K.Mukkanti, D.Shobha, M.Adharvana Chari, Prakash MMS Kinthada

An efficient synthesis of 4(3H)-quinazolinones by coupling of anthranilic acid, ortho esters and amines using Polymer supported ferric chloride catalyst under solvent free conditions is described. This new approach consistently has the advantage of excellent yields (80-97%) and short reaction times of 5-15 min.