Abstract
N-(4-Acetylphenyl)-2-cyanoacetamide as building block in heterocyclic synthesis: Synthesis and characterization of thiazole, pyridine, chromene and chromenopyridone
Author(s): Mohamed A.SalemDeferent types of thiazole derivatives were obtained via reaction of cyanoacetamide derivatve (1) with phenyl isothiocyanate and á- halocarbonyl compounds. Also, thiazole derivatives containing chromene moiety were synthesized through interaction of thiosemicarbazone derivative (10) with á-halocarbonyl compounds followed by cyclocondensation with salicyldehyde. In addition, deferent types of 3-cyanopyridine derivatives were obtained through reaction of (1) or (10) with some electrophilic reagents.
