Multicomponent catalytic synthesis of 1,2,3-triazoles by regio specific copper(I)-catalyzed 1,3-dipolar cycloadditions of terminal alkynes to azides

Author(s): Alireza Salimi Beni*, Saeideh Sajjadi

An efficient, facile, and practical liquid-phase combinatorial synthesis of various 1,2,3-triazoles was synthesizedfrom phenylacetylene, sodium azide and alkyl halide via a one-step process in the presence of a catalytic amount of a copper-salen complex in the water.

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