Abstract
Microwave assisted synthesis of 3-amino 1H-pyrazoles catalyzed by p-toluenesulphonic acid
Author(s): B.RamaRao,G.Venkateshwarlu, P.Sunitha,K.Shiva KumarAn efficient synthesis of 3-amino 1H-pyrazoles is described. Reaction of ï¢-keto-nitriles with hydrazines in the presence of catalytic amount of ptoluenesulphonic acid under microwave irradiation afforded the corresponding 3-amino 1H-pyrazole in excellent yields. The method is general for the preparation of a wide variety of 3-amino 1H-pyrazole.
