Microwave accelerated green synthesis of dihydropyrimidinones

Author(s): Mridula Phukan, Parthapratim Chaliha, Kalyan Jyoti Borah, Ashim Jyoti Thakur, Ruli Borah*

The effect of microwave irradiation(MWI) was investigated for Biginelli reaction of aromatic aldehyde, -ketoester, and (thio) urea without using organic solvent or catalyst under different microwave power level to the corresponding dihydropyrimidinones. These studies developed an improved microwave-assisted method for the synthesis of dihydropyrimi dinones in green condition with good yields.

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