All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission System of respective journal.


Formal Synthesis Of Tetramethyl 1-O-Methyl Curculigine Aglycon

Author(s): Dattatraya N. Bhangare, Vilas B. Mahale, Mahendra N, Lokhande, Rohit G. Shinde, Sneha C. Pisolkar, P. D. Pawar and Milind D. Nikalje.

 Curculigine isolated from the rhizomes of Curculigo capitulate and Curculigo recurvata plants of Hypoxidaceae family found potent against arrhythmia. Due to their biological importance we achieved the formal synthesis of Tetramethyl derivative of 1-O-Methyl curculigine Aglycon by applying Jacobsen’s hydrolytic and kinetic resolution strategy. Key intermediate was synthesized in four steps with 27% overall yield and 86% enantioselectivity.

Share this       
Google Scholar citation report
Citations : 565

Organic Chemistry: An Indian Journal received 565 citations as per Google Scholar report

Indexed In

  • CASS
  • Google Scholar
  • Open J Gate
  • China National Knowledge Infrastructure (CNKI)
  • Cosmos IF
  • Directory of Research Journal Indexing (DRJI)
  • Secret Search Engine Labs

View More