Abstract

Downstream Processing: Principles and Importance in Bioproduct Recovery

Author(s): Jonathan Lee

Downstream processing is a critical phase in biotechnological and biochemical production that involves the recovery, purification, and formulation of biologically derived products. It accounts for a significant portion of the overall production cost and directly influences product quality, safety, and efficacy. With the increasing demand for biopharmaceuticals, enzymes, and bio-based chemicals, efficient downstream processing has become essential for industrial success. This article provides an overview of downstream processing, focusing on its fundamental principles, commonly used techniques, and recent technological advancements. The role of downstream processing in ensuring product purity, regulatory compliance, and process sustainability is also discussed.