(Bromodimethyl)Sulfonium Bromide Mediated Rapid And Facile Protection Of Amines

Author(s): B.Vittal Rao, M.Shailaja, A.Manjula

A new clean protocol for protection of aryl and aliphatic amines with tbutoxycarbonyl (t-BOC) and benzyloxycarbonyl (Cbz) was developed using catalytic amount of (bromodimethyl) sulfonium bromide. The method is solvent free, mild and rapid protection of amines has been achieved in excellent yields.

Share this