(Bromodimethyl)Sulfonium Bromide Mediated Rapid And Facile Protection Of Amines

Author(s): B.Vittal Rao, M.Shailaja, A.Manjula

A new clean protocol for protection of aryl and aliphatic amines with tbutoxycarbonyl (t-BOC) and benzyloxycarbonyl (Cbz) was developed using catalytic amount of (bromodimethyl) sulfonium bromide. The method is solvent free, mild and rapid protection of amines has been achieved in excellent yields.

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