Anti-implantation activity of Terminalia bellirica bark extracts in female albino rats

Author(s): T.Vishwanatha, S.Satishagouda, J.Sharangouda Patil, B.Saraswati Patil

Ancient literature mentions the use of number of plants, plant preparations and their phytochemical constituents for fertility regulation. Some local contraceptive agents have also been described in Ayurvedic, Sidda and Unani texts. Documented experiments or clinical data are, however, lacking. Therefore, the present investigation was undertaken to discover the antiimplantation activity of benzene and ethanol extracts of graded doses of the barks of Terminalia bellirica. A strong antiimplantation (74.20% inhibition) activity was observed at the dose level of 25mg/100g body weight. Thus, the T. bellirica barks extract may be explored as a female contraceptive.

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