A study on antimicrobial activity of 1, 8-naphthyridines containing triazinanones, oxadiazinanones, pyrazolyl and substituted pyrimidines

E.Laxminarayana; M.Ranadheer Kumar; D.Ramesh; M.Thirumala Chary

Organic Chemistry: An Indian Journal
ISSN (PRINT): 0974-7516

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Abstract

A study on antimicrobial activity of 1, 8-naphthyridines containing triazinanones, oxadiazinanones, pyrazolyl and substituted pyrimidines

Author(s): E.Laxminarayana, M.Ranadheer Kumar, D.Ramesh, M.Thirumala Chary

The effect of substituted 1,8-naphthyridine derivatives has been investigated for their antimicrobial activity. Five bacteria Staphylococcus aureus, Klebsiella pneumoniae, Micrococcusluteus, Proteus mirabalis and Salmonella paratyphi. The antifungal activity of (IV) and (VI) have been investigated against two fungal species Fusarium chlamydosporium, Macrophomina phaseolina. Some of the tested compounds were found to be toxic against the bacteria and fungi.