A new method of deprotection for the hydroxide radicals: Boron trifluoride etherate/sodium iodide

Author(s): Yu-Qing Cao, Xiao-Jun Yang, Xiang-Tao Xu, Ding-Xiang Du, Li-Ya Xu, Fang-Rui Song

A new efficient method for dealkylation of ethers is reported. Ethers could transform into corresponding alcohols with boron trifluoride etherate and sodium iodide in acetonitrile after hydrolysis. This reaction can proceed at roomtemperature, and the yield is excellent.

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