Abstract

A new method for determination of fenoprofen in urine and human plasma by differential pulse adsorptive stripping voltammetry

Author(s): ShahryarAbbasi, Saeid Zadkhast, HosseinKhani

A novel selective and sensitive electrochemical method is developed for determination of fenoprofen by adsorptive stripping voltammetry (DPAdSV). Fenoprofen gave well resolved diffusion controlled cathodic peak at -0.989 V vs. Ag/AgCl reference electrode in phosphate buffer. Optimal conditions were obtained at pH 4.4, accumulation potential 0.15 V, accumulation time of 40 s, and scan rate of 120 mV/s. Under the optimized conditions, linear calibration curves were established for the concentration of fenoprofen in the range of 0.418-52.26 ì g/ml, with detection limit of 0.081ìg/ml. The relative standard deviation of the methodfor 10 runs at 0.418 and 4.18 µg/m lfenoprofen was 3.18%, 2.49%,, respectively. The method was applied to the determination of fenoprofen in various biological samples with satisfactory results.


Share this       

Share this Page.

Table of Contents

Flyer
izmir escort izmir escort bursa escort antalya escort izmir escort porno porno izle türk porno eskişehir escort bartın escort burdur escort izmir escort bursa escort porno indir izle istanbul escort istanbul escort bayan escort izmir