Abstract
A convenient methodology for the synthesis of functionalized nitrogen mustards
Author(s): A.V.Reddy, J.Gopalakrishna, Kelley T.Kovich, Subash C.Jonnalagadda, Venkatram R.MereddyA short protocol for the synthesis of functionalized bis(chloroethyl)amines (nitrogen mustards) has been described via the nucleophilic substitution of allylic bromides derived fromBaylis-Hillman alcoholswith diethanolamine followed by dichlorination.
