Abstract
A convenient and an efficient synthesis of 2,3-disubstituted derivatives of 8-methoxy-3-cyano-2-methylthio-4-oxo-4[H]- pyridimo [2,1-b][1,3]benzothiazole
Author(s): Vijay N.Bhosale, Sambhaji P.Vartale, Jagannath S.Jadhav, Prafullakumar A.Kulkarni, Ashok T.Suryawanshi8-Chloro-3-cyano-2-methylthio-4-oxo-4[H]-pyrimido-[2,1-b][1,3] benzothiazole has been prepared by the reaction of 6-Chloro-2-amino benzothiazole with ethyl-2-cyano-3,3-bismethylthioacrylate in the presence of diemethyl formamide and anhydrous potassiumcarbonate. Suspectibility of compound towards condensationwith different reagents like aryl amines, heteryl amines, phenols and compound containing active methylene group has been investigated.
