Abstract

2, 4, 6-trichloro-1, 3, 5-triazine (TCT) catalysed direct reductive amination of aldehydes using hantzsch dihydropyridine ester as a reducing agent

Author(s): Sandeep V.Shinde,, Kalpana M.Patil, Rajendra P.Pawar, Rajesh H.Tale

An efficient, rapid and environmentally benign approach for direct reductive amination of aldehydes and ketones is reported. Themild and economical process requires only catalytic amount of 2, 4, 6-trichloro-1, 3, 5-triazine (TCT) and utilizes Hantzsch ester for transfer hydrogenation and provides rapid access to the structurally diverse amines in high yields.