Abstract
Study On The Electrochemical Behaviour Of The Anticancer Herbal Drug Emodin
Author(s): Baoxian Ye, Liping Wang, Zongpei ZhangThe electrochemical behaviour of the anticancer herbal drug emodin was investigated by cyclic voltammetry (CV) at glassy carbon electrode. In 0.05 M NH3-NH4Cl (50% ethanol, pH 7.2) buffer solution, a pair of quasi-reversible redox peaks with peak potentials of Ep1 = -0.688V and Ep2 = -0.628V and an irreversible anodic peak, which was a typical anodic peak of emodin, with Ep3 = -0.235V were appeared at scan rate of 100 mV/s. The irreversible anodic peak currents are linearly relationship with emodin concentrations in the range of 8.9×10-8 M to 7.8×10-6 M with pre-concentration 80s under -0.620V. Using established method, the emodin in herbal drug was determined with satisfactory results and separation was unnecessary. Moreover, the electrode process dynamics parameters were investigated too by electrochemical techniques.
