All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission System of respective journal.

Abstract

Development and validation of anHPLCmethod for the analysis of nateglinide in pharmaceutical dosage forms

Author(s): K.Srinivasa Rao, K.Srinivas

A simple reverse phase HPLC method was developed for the determination of nateglinide present in pharmaceutical dosage forms. A Hypersil ODS C18, 4.6mm250mm, 5µm column with mobile phase acetonitrile: phosphate buffer pH-5.5,70:30%v/v was used. The flow rate was 1.0 ml/ min and effluent was monitored at 210 nm. Ezetemibe is used as internal standard. The retention times were 4.47min and 3.308min for nateglinide and ezetimibe respectively. The linearity range was found to be 0.5-200µg/ ml for nateglinide. The proposed method was also validated.


Share this       
Awards Nomination 20+ Million Readerbase

Table of Contents

Google Scholar citation report
Citations : 378

Analytical Chemistry: An Indian Journal received 378 citations as per Google Scholar report

Indexed In

  • CASS
  • Google Scholar
  • Open J Gate
  • China National Knowledge Infrastructure (CNKI)
  • CiteFactor
  • Cosmos IF
  • Electronic Journals Library
  • Directory of Research Journal Indexing (DRJI)
  • Secret Search Engine Labs
  • ICMJE

View More

Flyer