Toxicological assessment of reactive red 35 and its biodegraded products using cytogenotoxicity, oxidative stress and phytotoxicity studies

Author(s): Rakesh K.Soni, P.B.Acharya, H.A.Modi

Water-soluble azo dyes are extensively used in textile industries and known to be a major environmental pollutant. Toxicity analysis of the treated dye using Allium cepa root cells showed remarkable improvement in cell viability, root length, mitotic index and chromosomal aberrations than that of untreated RR35. Decreased genotoxicity potential as DNA damage in cells was also observed in biologically treated dye. Induced superoxide dismutase (SOD) activity and suppressed catalase (CAT) activity along with increased lipid peroxidation, and protein oxidation indicated oxidative stress in root cells exposed to the dye molecules. These symptoms were abridged in root cells treated with biologically treated dye solution, which indicates diminution of toxicity of the dye after treatment. Phytotoxicity studies further reflected the decreased in toxicity of the dye after biological treatment.

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