Background and Objective: Phenol is one of the serious pollutants from the chemical and petrochemical industries. This pollutant due to its convoluted structure is resistant to biodegradation. One of the methods that is useful to removal this pollutant is advanced oxidation (AOP). Materials and Methods: A laboratory scale study was done on a synthetic wastewater containing phenol. All experiments was done in batch conditions and effect of variables pH, amount of hydrogen peroxide, iron dosage, contact time and initial concentration on the phenol removal were tested. The remaining phenol concentration was measured using the DR- 5000 device. Results and Discussion: In order to effect of these parameters, the experiment was performance at pH 2 to 6, 5 to 45 ml of peroxide, time of 5 to 60 minutes with 2 to 15 g iron powder. The optimum pH, ratio of hydrogen, hydrogen, iron powder and time were 3, 15 mg/l, 8g and 5 minutes respectively. In order of COD test was done to confirm the complete mineralization and result shown that mineralization of phenol was not complete. Conclusion: According to the results of this study and high preference, Fenton-like process can be used for conversion organic resistant compounds to other compounds with lower toxicity.