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Investigations on phytochemical analysis and antifungal activity of Chromolena odorata (L) king and robinson on human dermatophytic fungi

Author(s): M.B.Chandrashekar, Raja Nayak, K.Bhagath, T.R.Prashith Kekuda

The present investigation highlights phytochemical screening and antifungal activity of Chromolena odorata kings and robinson. The shade dried plant materials (root and leaf) were subjected to soxhlet extraction using petroleum ether, ethanol and chloroform as solvents. The solvent extracts were subjected to preliminary phytochemical screening and in vitro antifungal activity against human dermatophytic fungi by Well diffusion method. Leaf extracts exhibited the presence ofmore phytoconstituents than root extracts.Marked antifungal activity was observed in case of leaf extracts. The antifungal activity could be due to the phytoconstituents present in the solvent extracts. Further studies in animal models could possibly reveal the potential of plant to inhibit fungal pathogens in vivo.

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