CNS depressant activity of Hibiscus mutabilis Linn. (Malvaceae) bark

Author(s): R.D.Bhalke, P.B.Ghogare, A.S.Girme, R.S.Jadhav, V.D.Tambe

Present study reports CNS depressant activity of petroleum ether, ethyl acetate and methanol extracts of Hibiscus mutabilis bark. Extracts were screened for CNS depressant activity by pentobarbitone-induced sleeping time and locomotor activity testing. Results indicate that petroleum ether extract showed best CNS depressant activity.

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