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 The efficiency of cancer treatments is, in the initial stages of testing, often measured by the ablation fraction of tumor mass (fractional kill). As CSCs form a minor proportion of the tumor, this may not necessarily choice for drugs that act specifically on the stem cells. The theory suggests that conventional chemotherapies kill differentiated or differentiating cells, which form the bulk of the tumor but do not generate new cells. A population of CSCs, which gave rise to it, could remain untouched and cause relapse. Stem cell transplants are most often used to help people with leukemia and lymphoma. They may also be recycled for neuroblastoma and multiple myeloma. Stem cell transplants for further varieties of cancer are being studied in clinical trials, which are research studies involving people.

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