Acta Chimica and Pharmaceutica Indica
ISSN: 2277-288X

Sick Sinus Syndrome

Sick sinus syndrome is associated with abnormal impulse initiation and propagation from the SAN. Patients affected by this disease have sinus bradycardia, sinus pauses or arrest, atrial chronotropic incompetence, and SAN exit block. Sick sinus node dysfunction occurs most commonly in older patients, but even healthy older patient show higher regularity and altered fractal scaling, consisting of a loss of complex variability. In the sick sinus patients, the average spread around the mean interval is higher than in control patients. Similar results were documented in dogs with sick sinus syndrome

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