Acta Chimica and Pharmaceutica Indica
ISSN: 2277-288X

Odontohypophosphatasia Open Access Journals

Odontohypophosphatasia is the mildest type of hypophosphatasia that shows as tooth dysplasia or potentially early loss of deciduous or changeless teeth. Likewise with all types of hypophosphatasia, the fundamental variation from the norm is a change in the ALPL quality that encodes for tissue vague antacid phosphatase. Hereditary testing joined with low serum antacid phosphatase action make the conclusion since the radiological appearances alone are not explicit. The main feature of odontohypophosphatasia is premature exfoliation of fully rooted primary teeth and/or severe dental caries. The anterior deciduous teeth are most commonly affected along with the incisors. X-rays reveal reduced alveolar bone, reduced thickness of dentin, and enlarged pulp chambers and root canals. Patients with other forms of HPP often have dental manifestations but these are always associated with skeletal abnormalities and other manifestations.

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