Immunodeficiency implies when the body's resistant reaction is diminished or missing. As the resistant framework shields the body from destructive substances called antigens like microorganisms, disease cells, blood or tissues from someone else and poisons, it is interceded by the invulnerable reaction that incorporates reactions by white platelets which is made out of neutrophils and lymphocytes. Neutrophils overwhelm the outside molecule and crush them by a procedure called phagocytosis. Lymphocytes can be isolated into two sorts: T lymphocytes and B lymphocytes. T lymphocytes legitimately assault antigens (cell insusceptibility). B lymphocytes produce antibodies (humoral resistance) that connect to the antigen or outside molecule and make phagocytes and body synthetic compounds, for example, supplement proteins, that helps in the obliteration of the antigen or remote molecule. In immunodeficiency, there is the disappointment of at least one pieces of the resistant framework. It very well may be partitioned into two classifications essential immunodeficiency and procured immunodeficiency. Essential immunodeficiency is brought about by inherent/acquired deformities and in essential immunodeficiency there is either lack in B cells, T cells or both B and T cells or because of flawed phagocytes. Though obtained immunodeficiency is brought about by an ailment that influences the resistant framework. There are sure tests that can analyze immunodeficiency issue. The tests that show immunodeficiency issue are low white platelet tally, low counter acting agent or immunoglobulin levels, low supplement levels. Immunodeficiency can be treated by quality treatment or bone marrow transplantation as no medication can be useful in this issue. A diary is a periodical distribution expected to additionally advance of science, typically by detailing new exploration.