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Simple Method for the Demonstration of Drug-Loaded Nano-Liposomes

Author(s): Riam Abu-Much, Naim Najami, Saba Hugerat and Muhamad Hugerat

A pioneering way for performing drug-loaded liposome nano-structures is presented. Aqueous solutions of liposome structures were prepared by a simple way and used as a model for exploring cell membrane structure and drug carriers. Drug solutions of Acamol and Optalgin were prepared, colored by food dye and then penetrated into the hydrophilic interior part of the liposome structure. In a second step of the experiment, the size of drug-loaded liposome structures were minimized from micro-scale to nanometer scale (400 nm, 100 nm) using Mini-Extruder apparatus.

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