7187379870

All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission System of respective journal.

Abstract

Quantitative estimation of wedelolactone in Eclipta alba hask using high performance liquid chromatography

Author(s): Purnima Hamrapurkar, Manasi Chachad, Mitesh Phale

Wedelolactone is a characterizing compound present in the plant Eclipta alba, used in viral hepatitis, liver diseases, skin and hair care. A simple, accurate and sensitive HPLC method was developed for estimation of wedelolactone, a furanocoumarin present as a major active constituent in the plant Eclipta alba. The chromatographic separation was carried out on RP C18 (Waters) column (2504.6 mm, 10m) using an isocratic mobile phase,Acetonitrile:Water (35:65%v/v) pumped at a flowrate of 1ml/min. The eluentwasmonitored at 351 nm. Themethod is specific and linear over the range of 300 ng/ml to 1500 ng/ml. The method was statistically validated for precision, accuracy, robustness and recovery. The HPLCmethod can be applied for identification and quantitation ofwedelolactone in herbal extracts of Eclipta alba.


Share this       
Google Scholar citation report
Citations : 1106

Natural Products: An Indian Journal received 1106 citations as per Google Scholar report

Indexed In

  • CASS
  • Google Scholar
  • Open J Gate
  • China National Knowledge Infrastructure (CNKI)
  • Cosmos IF
  • Directory of Research Journal Indexing (DRJI)
  • Secret Search Engine Labs
  • Scholar Article Impact Factor (SAJI))
  • ICMJE

View More

Flyer