Quantification Method Development and Validation for Analysis of Rivastigmine in Bulk and Pharmaceutical Dosage Form by RP-HPLC

Author(s): K. S. Nataraj, S. Suresh Kumar, M. Badrud Duza and D. B. Raju

A rapid and precise reverse phase high performance liquid chromatographic method has been developed for the estimation of Rivastigmine in its pur e form as well as in pharmaceutical dosage forms. Chromatography was carried out on Inertsil, C-18, 250 x 4.6 mm. 5 μ using a mixture of Phosphate buffer and Acetonitrile (70 : 30 v/v) as the mobile phase at a flow rate of 1.0 mL/min the detection was done by UV at 217nm. The retention time of the drug was 3.66 ± 0.25 min min. The method produced linear responses in the concentration range of 10-100 μ g/mL of Rivastigmine. The method was found to be reproducible for analysis of the drug in tablet dosage forms

Share this       
izmir escort izmir escort bursa escort antalya escort izmir escort porno porno izle türk porno eskişehir escort bartın escort burdur escort izmir escort bursa escort porno indir izle escort izmir