Abstract

Phyto-chemical analysis, radical scavenging and cytotoxic activities of Fragaria nubicola from Kashmir, India

Author(s): Mohd Yousuf Dar

Objectives: Phytochemical analysis and biological activities of Fragaria nubicola. Methods: The powdered plant material of Fragaria nubicola was successively extracted with dichloromethane, ethyl acetate, methanol and water. The radical scavenging activity of methanolic extract was tested using 1, 1-diphenyl-2-picrylhydrazyl radical by TLC and spectrophotometric method. Methanol and dichloro-methane extract was tested against Leukemia (THP-1), Lung (A-549), Colon (Caoc-2) and Liver (HEP-2) cell lines at 50 µg/ml, respectively. Results: The phytochemical analysis of methnolic extract revealed the presence of flavonoids, tannins, saponins and phenols. The methanolic extract tested showed 71±0.2% radical scavenging activity at 40 µg/ml. The results of cytotoxic activity of methanolic and dichloro-methane extract showed that methanolic extract was only active against the THP-1 and HEP-2 cell cultures. Discussion: Fragaria nubicola showed radical scavenging activity due to flavonoids, tannins, saponins and phenols. Conclusion: The extract could be used to control various oxidative stress related disorders.


Share this       
izmir escort izmir escort bursa escort antalya escort izmir escort porno porno izle türk porno eskişehir escort bartın escort burdur escort izmir escort bursa escort porno indir izle istanbul escort istanbul escort bayan escort izmir