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Physicochemical Investigation of Primary Changes in DNA Adjusted with Glucose

Author(s): Amenaghawon Akpa

Progressed glycation final results (AGEs) bring about the non-enzymatic changes of natural macromolecules by decreasing sugars. The AGE development process (Maillard response) begins with the arrangement of Schiff bases and the amadori items that are created in the response of lessening sugars with proteins, lipids, and DNA. Amassing of AGEs under in vivo conditions has been involved in optional difficulties of diabetes in hyperglycemic conditions.

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