Nuclear Magnetic Resonance SpectroscopyvAuthor(s): Aakshi Kainthola
NMR spectroscopy is an analytical chemistry technique for measuring the quantity and purity of a sample, as well as its molecular structure, that is used in quality control and research. NMR, for example, can be used to examine mixtures of known substances quantitatively. NMR can be used to identify unknown chemicals by comparing them to spectral libraries or inferring their basic structure. For tiny compounds, NMR spectra are distinctive, well-resolved, analytically tractable, and typically very predictable. Different functional groups can clearly be distinguished, and even identical functional groups with different adjacent substituents can provide distinct signals. For identifying substances, NMR has essentially supplanted traditional wet chemistry techniques such as colour reagents or standard chromatography. NMR's timescale is relatively long, making it unsuitable for viewing quick processes, as it only produces an averaged spectrum. Although huge amounts of contaminants appear on an NMR spectrum, better methods for identifying impurities exist because NMR is inherently insensitive - though sensitivity increases at higher frequencies.