All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission System of respective journal.

Abstract

Limonoids as antidyslipidemic from the fruits of Xylocarpus molluccensis

Author(s): Vijai Lakshmi, Anju Puri

The ocean offers a rich source of structurally unique molecules providing novel plate form for drug discovery. The 95% ethanol extract of the epicarp of the fruits of X. molluccensis given orally at a dose of 500mg/kg showed significant antidyslipidemic activity in hamster model. Among the four fractions tested the chloroform soluble fraction showed highly significant lipid lowering activity at 50mg/kg. Further purification of chloroform fraction yielded four compounds. Out of four compounds bioevaluated, only one compound showed promising activity even at 25mg/ kg. dose.


Share this