A Comprehensive Review on Gastro Retentive Drug Delivery System

Author(s): Marinaganti Rajeev Kumar, Bonthu Satyanarayana, Nagakanyaka Devi Paladugu, Neerukondavamsi, Sheik Muddasar, Shaik Irfan Pasha, Spandana Vemireddy and Deepthi Poloju

In recent years several advancements has been made in research and development of oral drug delivery system. Concept of novel drug delivery system arose to overcome certain aspect related to physicochemical properties of drug molecule and the related formulations. Purpose of this review is to compile the recent literature with special focus on various gastro retentive approaches that have recently become leading methodologies in the field of site-specific orally administered controlled release drug delivery. In order to understand various physiological difficulties to achieve gastric retention, we have summarized factors influencing gastric retention and also included various strategies for gastric retention. GRDDS has become leading methodology in site specific orally administered controlled release drug delivery system. Various drugs, which are unstable in alkaline pH, soluble in acidic pH, having narrow absorption window, site of action specific to stomach can be developed by using this technique.

Share this       

Recommended Conferences

izmir escort izmir escort bursa escort antalya escort izmir escort porno porno izle türk porno eskişehir escort bartın escort burdur escort havalandırma izmir escort bursa escort porno indir izle escort izmir