The reinforced concrete (RC) moment-resisting frames with masonry infill walls is widely used in buildings. In most cases the masonry Infill is neglected from the design which causes a negative impact in the framed system during a seismic behavior. In this study, two-bay and three-storeyed RC Bare Frame (BF), RC Infill frame (IF) with Cement mortar (CM) interface combinations scaled to a factor (1:6) are analyzed. The influence of constructional details of infill walls on the seismic behavior of RC frames is analyzed. Literature survey carried out in this area indicates that not much work has been done in studying the influence of interface material's properties on the behavior of IF frame. The objective is achieved by analytical studies. To investigate this, we modelled the behavior of frame structures with masonry IF in three ways such as a linear method and Pushover (PO) method. It is found that with the addition of masonry infill wall rigidly connected to the frame, the lateral strength, the stiffness of the BF RC frame increase significantly while the displacement ductility ratio decreases significantly. Numerical simulation of the BF and the IF frames is done with SAP2000 (Structural Analysis Package) a FEM (Finite Element Method) based software.